Even once you get past the different software used there are filters and postwork which can greatly affect the look.
Lets have a little comparision of a few comics. I'm giving some information about software used but forgive me if there are inaccuracies.
A deviant mind
Fairly close to how I work, I believe. Raw renders done with the inbuilt render engine of daz studio some postwork when needed.

Batteen (various shorts)
daz studio ( I think)

Bhaddland
I believe this is also done with daz studio, not sure which version. I don't know what filter oreffects is done to the pages.

Crimson dark

rendered in cinema 4D with extensive postwork.
Dark sisters
Death porn
Rendered in Carrara.

Found art (Mellandra's Galaxy)
Now done in daz studio 4, although I have no idea of what filter/effect is used.

Riven sol
Poser with etensive postwork

Shaman quest
Made with poser(pro 2012?) again it is mostly raw renders with postwork when required.
